EDG-8 rabbit pAb
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e. g. EDG1; MIM 601974) are S1P receptors; others (e. g. EDG2; MIM 602282) are LPA receptors. [supplied by OMIM, Mar 2008],
Product Specifications
Background
Synonyms
Gene ID
53637
UniProt
Q9H228
Cellular Locus
Cell membrane; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human EDG8. AA range:335-384
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC, IF, ELISA
Validated Applications
IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6624-1.pdf
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
Gene ID (Human)
53637
SwissProt (Human)
Q9H228
Available Sizes
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