PLC β2 rabbit pAb

Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate + H (2)O = 1D-myo-inositol 1, 4, 5-trisphosphate + diacylglycerol. Cofactor: Binds 1 calcium ion per subunit. function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. miscellaneous: The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16. similarity: Contains 1 C2 domain. similarity: Contains 1 PI-PLC X-box domain. similarity: Contains 1 PI-PLC Y-box domain. subunit: Interacts with RAC1.