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CYB5R1 rabbit pAb

Catalytic activity: NADH + 2 ferriCytochrome b5 = NAD (+) + H (+) + 2 ferroCytochrome b5. Cofactor: FAD. function: NADH-Cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. similarity: Belongs to the flavoprotein pyridine nucleotide Cytochrome reductase family. similarity: Contains 1 FAD-binding FR-type domain. tissue specificity: Widely expressed.

Product Specifications

Background

Catalytic activity:NADH + 2 ferricytochrome b5 = NAD (+) + H (+) + 2 ferrocytochrome b5., cofactor:FAD., function:NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction., similarity:Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family., similarity:Contains 1 FAD-binding FR-type domain., tissue specificity:Widely expressed.

Synonyms

CYB5R1; NQO3A2; NADH-cytochrome b5 reductase 1; b5R.1; Humb5R2; NAD(P)H:quinone oxidoreductase type 3 polypeptide A2

Gene ID

51706

UniProt

Q9UHQ9

Cellular Locus

Membrane ; Single-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CYB5R1. AA range:9-58

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

34kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6560-1.pdf

Observed Molecular Weight

34 kD

Subcellular Location

Membrane ; Single-pass membrane protein .

Other Product Names

CYB5R1; NQO3A2; NADH-cytochrome b5 reductase 1; b5R.1; Humb5R2; NAD (P) H:quinone oxidoreductase type 3 polypeptide A2

Gene ID (Human)

51706

SwissProt (Human)

Q9UHQ9

Available Sizes

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