Complement factor D

Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies[1].

Product Specifications

CAS Number

[37213-56-2]

UNSPSC

12352204

Target

Ser/Thr Protease

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/complement-factor-d.html

Solubility

10 mM in DMSO

Smiles

[ComplementfactorD]

References & Citations

[1]Barratt J, et al. Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway. Front Immunol. 2021 Sep 9;12:712572.