Sar1B rabbit pAb

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010],

Product Specifications

Background

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD) . Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

UniProt

Q9Y6B6

Swiss Prot

Q9Y6B6

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human SAR1B. AA range:111-160

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

22kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

22kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus, Golgi stack membrane ; Peripheral membrane protein . Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. .