What is the catalog number for PAKγ rabbit pAb?

The catalog number for PAKγ rabbit pAb is ES6471.

What sizes are available for PAKγ rabbit pAb?

PAKγ rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does PAKγ rabbit pAb come in?

PAKγ rabbit pAb is available in 2 different pack sizes.

Is PAKγ rabbit pAb in stock?

PAKγ rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAKγ rabbit pAb?

PAKγ rabbit pAb is manufactured by ELK.

What is the estimated delivery time for PAKγ rabbit pAb?

Estimated delivery time for PAKγ rabbit pAb is approximately 10 business day(s), depending on your location.

PAKγ rabbit pAb

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]

UniProt

Q13177

Swiss Prot

Q13177

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PAK2. AA range:5-54

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

60kD

Fragment

IgG

Subcellular Location

[Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.