Trk B (phospho Tyr516) rabbit pAb
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
Product Specifications
Background
Product Name Alternative
UniProt
Q16620
Swiss Prot
Q16620
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr515. AA range:481-530
Target
Trk B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
145kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
145kD
Fragment
IgG
Subcellular Location
Other Product Names
Gene ID (Human)
4915
Available Sizes
Frequently Asked Questions
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