NPY1-R rabbit pAb
This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013],
Product Specifications
Background
Synonyms
NPY1R; NPYR; NPYY1; Neuropeptide Y receptor type 1; NPY1-R
Gene ID
4886
UniProt
P25929
Cellular Locus
Cell membrane; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human NPY1R. AA range:221-270
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IF, ELISA
Validated Applications
WB,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
48kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6415-1.pdf
Observed Molecular Weight
48 kD
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
NPY1R; NPYR; NPYY1; Neuropeptide Y receptor type 1; NPY1-R
Gene ID (Human)
4886
SwissProt (Human)
P25929
Available Sizes
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