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CNOT2 rabbit pAb

CCR4-NOT transcription complex subunit 2 (CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010],

Product Specifications

Background

CCR4-NOT transcription complex subunit 2 (CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Synonyms

CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2

Gene ID

4848

UniProt

Q9NZN8

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CNOT2. AA range:67-116

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

46kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6404-1.pdf

Observed Molecular Weight

46 kD

Subcellular Location

Cytoplasm . Nucleus .

Other Product Names

CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2

Gene ID (Human)

4848

SwissProt (Human)

Q9NZN8

Available Sizes

Curated Selection

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