Myosin Id rabbit pAb

Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. similarity: Contains 1 myosin head-like domain. similarity: Contains 2 IQ domains. subunit: Binds calmodulin through its IQ motifs. tissue specificity: Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen.

Product Specifications

Background

Function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments., similarity:Contains 1 myosin head-like domain., similarity:Contains 2 IQ domains., subunit:Binds calmodulin through its IQ motifs., tissue specificity:Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen.

UniProt

O94832

Swiss Prot

O94832

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MYO1D. AA range:825-874

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm . Perikaryon . Cell projection, dendrite . Early endosome . Cytoplasm, cell cortex . Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles. .