B-Myb (phospho Ser577) rabbit pAb
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013],
Product Specifications
Background
Synonyms
MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2
Gene ID
4605
UniProt
P10244
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human B-Myb around the phosphorylation site of Ser577/581. AA range:551-600
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IF, ELISA
Validated Applications
WB,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
80kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6302-1.pdf
Observed Molecular Weight
80 kD
Subcellular Location
Nucleus.
Other Product Names
MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2
Gene ID (Human)
4605
SwissProt (Human)
P10244
Available Sizes
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