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MYBPC1 rabbit pAb

This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Product Name Alternative

MYBPC1; MYBPCS; Myosin-binding protein C; slow-type; Slow MyBP-C; C-protein, skeletal muscle slow isoform

UniProt

Q00872

Swiss Prot

Q00872

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MYBPC1. AA range:218-267

Target

MYBPC1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

120kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

120kD

Fragment

IgG

Subcellular Location

Cytosol, myofibril, myosin filament

Other Product Names

MYBPC1; MYBPCS; Myosin-binding protein C; slow-type; Slow MyBP-C; C-protein, skeletal muscle slow isoform

Gene ID (Human)

4604

Available Sizes

Frequently Asked Questions

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