A-Myb rabbit pAb
Function: Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells. similarity: Contains 3 HTH myb-type DNA-binding domains. subunit: Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2. tissue specificity: Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
Product Specifications
Background
Product Name Alternative
MYBL1; AMYB; Myb-related protein A; A-Myb; Myb-like protein 1
UniProt
P10243
Swiss Prot
P10243
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280
Target
A-Myb
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
MYBL1; AMYB; Myb-related protein A; A-Myb; Myb-like protein 1
Gene ID (Human)
4603
Available Sizes
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