MxB rabbit pAb

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Product Name Alternative

MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein

UniProt

P20592

Swiss Prot

P20592

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human MxB.

Target

MxB

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

82kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

82kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding.

Other Product Names

MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein