MAZ rabbit pAb

Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. similarity: Contains 6 C2H2-type zinc fingers. subcellular location: In brains of Alzheimer disease patients, present in a plaque-like structures. subunit: Interacts with BPTF. tissue specificity: Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).

Product Specifications

Background

Function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors., similarity:Contains 6 C2H2-type zinc fingers., subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures., subunit:Interacts with BPTF., tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level) .

UniProt

P56270

Swiss Prot

P56270

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

48kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

48kD

Fragment

IgG

Subcellular Location

Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.

Other Product Names

MAZ; ZNF801; Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Transcription factor Zif87; ZF87; Zinc finger protein 801