MAZ rabbit pAb
Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. similarity: Contains 6 C2H2-type zinc fingers. subcellular location: In brains of Alzheimer disease patients, present in a plaque-like structures. subunit: Interacts with BPTF. tissue specificity: Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Product Specifications
Background
Synonyms
Gene ID
4150
UniProt
P56270
Cellular Locus
Nucleus. In brains of Alzheimer disease patients, present in a plaque-like structures.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA, IHC
Validated Applications
WB,ELISA,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
48kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6197-1.pdf
Observed Molecular Weight
48 kD
Subcellular Location
Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.
Other Product Names
Gene ID (Human)
4150
SwissProt (Human)
P56270
Available Sizes
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