MARK1/2/3/4 (phospho Thr215) rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. enzyme regulation: Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39. function: May play a role in cytoskeletal stability. similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. similarity: Contains 1 KA1 (kinase-associated) domain. similarity: Contains 1 protein kinase domain. similarity: Contains 1 UBA domain. subcellular location: Appears to localize to an intracellular network. tissue specificity: Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
Product Specifications
Background
Synonyms
Gene ID
4139/2011/4140/57787
UniProt
Q9P0L2/Q7KZI7/P27448/Q96L34
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4 around the phosphorylation site of Thr215. AA range:181-230
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC, IF, ELISA
Validated Applications
IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6191-1.pdf
Subcellular Location
Other Product Names
Gene ID (Human)
4139/2011/4140/57787
SwissProt (Human)
Q9P0L2/Q7KZI7/P27448/Q96L34
Available Sizes
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