MARCKS (phospho Ser159) rabbit pAb
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
P29966
Swiss Prot
P29966
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser158. AA range:126-175
Target
MARCKS
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .
Other Product Names
Gene ID (Human)
4082
Available Sizes
Frequently Asked Questions
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