TM4SF1 rabbit pAb
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P30408
Swiss Prot
P30408
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human T4S1. AA range:1-50
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519) . .
Other Product Names
TM4SF1; M3S1; TAAL6; Transmembrane 4 L6 family member 1; Membrane component chromosome 3 surface marker 1; Tumor-associated antigen L6
Gene ID (Human)
4071
Available Sizes
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