LRP3 rabbit pAb
Function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. similarity: Belongs to the LDLR family. similarity: Contains 2 CUB domains. similarity: Contains 4 LDL-receptor class A domains. subunit: Binds GGA1 and GGA2. tissue specificity: Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
Product Specifications
Background
Synonyms
LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105
Gene ID
4037
UniProt
O75074
Cellular Locus
Membrane ; Single-pass type I membrane protein. Membrane, coated pit.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
80kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6138-1.pdf
Observed Molecular Weight
80 kD
Subcellular Location
Membrane ; Single-pass type I membrane protein . Membrane, coated pit .
Other Product Names
LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105
Gene ID (Human)
4037
SwissProt (Human)
O75074
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
