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LRP3 rabbit pAb

Function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. similarity: Belongs to the LDLR family. similarity: Contains 2 CUB domains. similarity: Contains 4 LDL-receptor class A domains. subunit: Binds GGA1 and GGA2. tissue specificity: Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.

Product Specifications

Background

Function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro., similarity:Belongs to the LDLR family., similarity:Contains 2 CUB domains., similarity:Contains 4 LDL-receptor class A domains., subunit:Binds GGA1 and GGA2., tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.

Synonyms

LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105

Gene ID

4037

UniProt

O75074

Cellular Locus

Membrane ; Single-pass type I membrane protein. Membrane, coated pit.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

80kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6138-1.pdf

Observed Molecular Weight

80 kD

Subcellular Location

Membrane ; Single-pass type I membrane protein . Membrane, coated pit .

Other Product Names

LRP3; Low-density lipoprotein receptor-related protein 3; LRP-3; 105 kDa low-density lipoprotein receptor-related protein; hLRp105

Gene ID (Human)

4037

SwissProt (Human)

O75074

Available Sizes

Curated Selection

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