Cleaved-Kininogen-1 HC (K380) rabbit pAb
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],
Product Specifications
Background
Product Name Alternative
UniProt
P01042
Swiss Prot
P01042
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Cleaved-Kininogen-1 HC (K380) . at AA range: 300-380
Target
Kininogen 1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
41kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
41kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space.
Other Product Names
Gene ID (Human)
3827
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Human KIR2DS4 (Killer Cell Immunoglobulin Like Receptor 2DS4) ELISA Kit
Human KIR2DS4 (Killer Cell Immunoglobulin Like Receptor 2DS4) ELISA Kit
Human KIR2DS4 (Killer Cell Immunoglobulin Like Receptor 2DS4) ELISA Kit