JAK3 (phospho Tyr785) rabbit pAb
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in Cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK
UniProt
P52333
Swiss Prot
P52333
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785. AA range:751-800
Target
JAK3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
125kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
125kD
Fragment
IgG
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm .
Other Product Names
JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK
Gene ID (Human)
3718
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
