JAK2 (phospho Tyr221) rabbit pAb
This gene product is a protein tyrosine kinase involved in a specific subset of Cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
O60674
Swiss Prot
O60674
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr221. AA range:191-240
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .
Other Product Names
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene ID (Human)
3717
Available Sizes
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