JAK2 (phospho Tyr221) rabbit pAb
This gene product is a protein tyrosine kinase involved in a specific subset of Cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene ID
3717
UniProt
O60674
Cellular Locus
Endomembrane system ; Peripheral membrane protein. Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr221. AA range:191-240
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
130kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5970-1.pdf
Observed Molecular Weight
130 kD
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .
Other Product Names
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene ID (Human)
3717
SwissProt (Human)
O60674
Available Sizes
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