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IRS-1 (phospho Ser323) rabbit pAb

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],

Product Specifications

Background

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

Product Name Alternative

IRS1; Insulin receptor substrate 1; IRS-1

UniProt

P35568

Swiss Prot

P35568

Reactivity

Human; Mouse; Rat; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser323. AA range:289-338

Target

IRS-1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

170kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

170kD

Fragment

IgG

Subcellular Location

Nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle

Other Product Names

IRS1; Insulin receptor substrate 1; IRS-1

Gene ID (Human)

3667

Available Sizes

Curated Selection

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