IRF-3 (phospho Ser396) rabbit pAb
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
Product Specifications
Background
Product Name Alternative
IRF3; Interferon regulatory factor 3; IRF-3
UniProt
Q14653
Swiss Prot
Q14653
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser396. AA range:362-411
Target
IRF-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
48-55kd
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48-55kd
Fragment
IgG
Subcellular Location
Other Product Names
IRF3; Interferon regulatory factor 3; IRF-3
Gene ID (Human)
3661
Available Sizes
Frequently Asked Questions
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