IRAK-1 (phospho Ser376) rabbit pAb
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1
Gene ID
3654
UniProt
P51617
Cellular Locus
Cytoplasm. Nucleus. Lipid droplet. Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity)..
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Ser376. AA range:342-391
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC, IF, ELISA
Validated Applications
IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5916-1.pdf
Subcellular Location
Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity) . .
Other Product Names
IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1
Gene ID (Human)
3654
SwissProt (Human)
P51617
Available Sizes
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