IRAK-1 (phospho Thr100) rabbit pAb
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P51617
Swiss Prot
P51617
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr100. AA range:66-115
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
77kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
77kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity) . .
Other Product Names
IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1
Gene ID (Human)
3654
Available Sizes
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