Synaptotagmin X rabbit pAb

Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. function: May be involved in Ca (2+)-dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. similarity: Belongs to the synaptotagmin family. similarity: Contains 2 C2 domains. subunit: Homodimer. Can also form heterodimers. tissue specificity: Expressed only in pancreas, lung and kidney.

Product Specifications

Background

Cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains., function:May be involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis., similarity:Belongs to the synaptotagmin family., similarity:Contains 2 C2 domains., subunit:Homodimer. Can also form heterodimers., tissue specificity:Expressed only in pancreas, lung and kidney.

Product Name Alternative

SYT10; Synaptotagmin-10; Synaptotagmin X; SytX

UniProt

Q6XYQ8

Swiss Prot

Q6XYQ8

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460

Target

Synaptotagmin X

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .