CD50 (phospho Ser518) rabbit pAb
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Product Specifications
Background
Synonyms
ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50
Gene ID
3385
UniProt
P32942
Cellular Locus
Membrane; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CD50/ICAM-3 around the phosphorylation site of Ser518. AA range:484-533
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
42-60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5810-1.pdf
Observed Molecular Weight
42 - 60 kD
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD antigen CD50
Gene ID (Human)
3385
SwissProt (Human)
P32942
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit anti-Drosophila melanogaster (Fruit fly) ac Polyclonal Antibody
Recombinant Prochlorococcus sp. Urease accessory protein UreE (ureE)
Recombinant Prochlorococcus sp. Urease accessory protein UreE (ureE)
Recombinant Prochlorococcus sp. Urease accessory protein UreE (ureE)
Recombinant Prochlorococcus sp. Urease accessory protein UreE (ureE)