ICAM-2 rabbit pAb
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
ICAM2; Intercellular adhesion molecule 2; ICAM-2; CD antigen CD102
Gene ID
3384
UniProt
P13598
Cellular Locus
Membrane ; Single-pass type I membrane protein. Cell projection, microvillus. Co-localizes with RDX, EZR and MSN in microvilli..
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ICAM2. AA range:151-200
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
30kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5808-1.pdf
Observed Molecular Weight
30 kD
Subcellular Location
Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Co-localizes with RDX, EZR and MSN in microvilli. .
Other Product Names
ICAM2; Intercellular adhesion molecule 2; ICAM-2; CD antigen CD102
Gene ID (Human)
3384
SwissProt (Human)
P13598
Available Sizes
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