SPDMV
SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].
Product Specifications
CAS Number
[890409-85-5]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spdmv.html
Purity
99.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(SSC1=NC=CC=C1)(C)CCC(ON2C(CCC2=O)=O)=O
Molecular Formula
C15H18N2O4S2
Molecular Weight
354.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Daniel Teufel, et al. Bicyclic peptide-toxin conjugates specific for mt1-mmp. WO2017191460A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Disulfide Cleavable Linker
Available Sizes
Curated Selection
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