Glucuronidase β rabbit pAb
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4, 6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome. [provided by RefSeq, May 2014],
Product Specifications
Background
Synonyms
GUSB; Beta-glucuronidase; Beta-G1
Gene ID
2990
UniProt
P08236
Cellular Locus
Lysosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GUSB. AA range:321-370
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5695-1.pdf
Observed Molecular Weight
78 kD
Subcellular Location
Lysosome.
Other Product Names
GUSB; Beta-glucuronidase; Beta-G1
Gene ID (Human)
2990
SwissProt (Human)
P08236
Available Sizes
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