Glucuronidase β rabbit pAb
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4, 6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome. [provided by RefSeq, May 2014],
Product Specifications
Background
UniProt
P08236
Swiss Prot
P08236
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GUSB. AA range:321-370
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
78kD
Fragment
IgG
Subcellular Location
Lysosome.
Other Product Names
GUSB; Beta-glucuronidase; Beta-G1
Gene ID (Human)
2990
Available Sizes
Frequently Asked Questions
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