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LOST1 rabbit pAb

Developmental stage: Expressed in fetal brain. function: May be involved in fat metabolism. similarity: Belongs to the CD225 family. tissue specificity: Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.

Product Specifications

Background

Developmental stage:Expressed in fetal brain., function:May be involved in fat metabolism., similarity:Belongs to the CD225 family., tissue specificity:Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.

Synonyms

TUSC5; IFITMD3; LOST1; Tumor suppressor candidate 5; Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1

Gene ID

286753

UniProt

Q8IXB3

Cellular Locus

Cell membrane ; Single-pass membrane protein. Endomembrane system ; Single-pass membrane protein. Cytoplasm, perinuclear region. Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TUSC5. AA range:1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

22kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5621-1.pdf

Observed Molecular Weight

22 kD

Subcellular Location

Cell membrane ; Single-pass membrane protein . Endomembrane system ; Single-pass membrane protein . Cytoplasm, perinuclear region . Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation. .

Other Product Names

TUSC5; IFITMD3; LOST1; Tumor suppressor candidate 5; Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1

Gene ID (Human)

286753

SwissProt (Human)

Q8IXB3

Available Sizes

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