GPR17 rabbit pAb
Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G (i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
Product Specifications
Background
UniProt
Q13304
Swiss Prot
Q13304
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12
Gene ID (Human)
2840
Available Sizes
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