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Gγ 5 rabbit pAb

G protein subunit gamma 5 (GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al. 1995) [PubMed 7606925]. [supplied by OMIM, Nov 2010],

Product Specifications

Background

G protein subunit gamma 5 (GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]

Product Name Alternative

GNG5; GNGT5; Guanine nucleotide-binding protein G (I) /G (S) /G (O) subunit gamma-5

UniProt

P63218

Swiss Prot

P63218

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59

Target

Gγ 5

Clonality

Polyclonal

Source

Rabbit

Applications

IF; ELISA

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Other Product Names

GNG5; GNGT5; Guanine nucleotide-binding protein G (I) /G (S) /G (O) subunit gamma-5

Gene ID (Human)

2787

Available Sizes

Curated Selection

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