STK36 rabbit pAb
This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011],
Product Specifications
Background
UniProt
Q9NRP7
Swiss Prot
Q9NRP7
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human STK36. AA range:387-436
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
170kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
170kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, cilium axoneme . Low levels also present in the nucleus. .
Other Product Names
STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog
Gene ID (Human)
27148
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
OR2W3, CT (OR2W3, OR2W3P, OR2W8P, Olfactory receptor 2W3, Olfactory receptor 2W8, Olfactory receptor OR1-49)
