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Dkk-3 rabbit pAb

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

UniProt

Q9UBP4

Swiss Prot

Q9UBP4

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DKK3. AA range:111-160

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

45kD

Storage Conditions

-20°C/1 year

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5541-1.pdf

Observed Molecular Weight

45kD

Fragment

IgG

Subcellular Location

Secreted.

Other Product Names

DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

Gene ID (Human)

27122

Available Sizes

Curated Selection

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