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Dkk-3 rabbit pAb

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Synonyms

DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

Gene ID

27122

UniProt

Q9UBP4

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DKK3. AA range:111-160

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

45kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5541-1.pdf

Observed Molecular Weight

45 kD

Subcellular Location

Secreted.

Other Product Names

DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3

Gene ID (Human)

27122

SwissProt (Human)

Q9UBP4

Available Sizes

Curated Selection

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