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SERGEF rabbit pAb

Function: Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 7 RCC1 repeats. subunit: Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.

Product Specifications

Background

Function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 7 RCC1 repeats., subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.

Synonyms

SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein

Gene ID

26297

UniProt

Q9UGK8

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

50kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5490-1.pdf

Observed Molecular Weight

50 kD

Subcellular Location

Cytoplasm . Nucleus .

Other Product Names

SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein

Gene ID (Human)

26297

SwissProt (Human)

Q9UGK8

Available Sizes

Curated Selection

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