NOC2L rabbit pAb

NOC2 like nucleolar associated transcriptional repressor (NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al. 2005 [PubMed 16322561]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

NOC2 like nucleolar associated transcriptional repressor (NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]) .[supplied by OMIM, Mar 2008]

UniProt

Q9Y3T9

Swiss Prot

Q9Y3T9

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

85kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

85kD

Fragment

IgG

Subcellular Location

Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.