MIP-T3 rabbit pAb

Function: Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. similarity: Belongs to the TRAF3IP1 family. subcellular location: Microtubules. subunit: Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1. tissue specificity: Ubiquitous.

Product Specifications

Background

Function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules., similarity:Belongs to the TRAF3IP1 family., subcellular location:Microtubules., subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1., tissue specificity:Ubiquitous.

UniProt

Q8TDR0

Swiss Prot

Q8TDR0

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

78kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

78kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900) . In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268) . .

Other Product Names

TRAF3IP1; MIPT3; TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3; MIP-T3