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GPR124 rabbit pAb

Caution: It is uncertain whether Met-1 or Met-8 is the initiator. Domain: Binds to DLG1 through its PDZ-binding motif. function: Orphan receptor. similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. similarity: Contains 1 GPS domain. similarity: Contains 1 Ig-like (immunoglobulin-like) domain. similarity: Contains 5 LRR (leucine-rich) repeats. subunit: Interacts with DLG1. tissue specificity: Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.

Product Specifications

Background

Caution:It is uncertain whether Met-1 or Met-8 is the initiator., domain:Binds to DLG1 through its PDZ-binding motif., function:Orphan receptor., similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily., similarity:Contains 1 GPS domain., similarity:Contains 1 Ig-like (immunoglobulin-like) domain., similarity:Contains 5 LRR (leucine-rich) repeats., subunit:Interacts with DLG1., tissue specificity:Expressed in endothelial cells (at protein level) . Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.

Synonyms

GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5

Gene ID

25960

UniProt

Q96PE1

Cellular Locus

Cell membrane ; Multi-pass membrane protein. Cell projection, filopodium. Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR124. AA range:1151-1200

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IF, ELISA

Validated Applications

WB,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

145kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5457-1.pdf

Observed Molecular Weight

145 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cell projection, filopodium . Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. .

Other Product Names

GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5

Gene ID (Human)

25960

SwissProt (Human)

Q96PE1

Available Sizes

Curated Selection

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