T2R45 rabbit pAb
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli. similarity: Belongs to the G-protein coupled receptor T2R family. tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Product Specifications
Background
Product Name Alternative
TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59
UniProt
P59539
Swiss Prot
P59539
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TAS2R45. AA range:221-270
Target
T2R45
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Other Product Names
TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59
Gene ID (Human)
259291
Available Sizes
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