What is the catalog number for PKD2 rabbit pAb?

The catalog number for PKD2 rabbit pAb is ES5443.

What sizes are available for PKD2 rabbit pAb?

PKD2 rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does PKD2 rabbit pAb come in?

PKD2 rabbit pAb is available in 2 different pack sizes.

Is PKD2 rabbit pAb in stock?

PKD2 rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PKD2 rabbit pAb?

PKD2 rabbit pAb is manufactured by ELK.

What is the estimated delivery time for PKD2 rabbit pAb?

Estimated delivery time for PKD2 rabbit pAb is approximately 10 business day(s), depending on your location.

PKD2 rabbit pAb

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt

Q9BZL6

Swiss Prot

Q9BZL6

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PKD2. AA range:829-878

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

96kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

96kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cell membrane . Nucleus . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .