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Rad54B rabbit pAb

The RAD54 homolog B encoded by RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

Product Specifications

Background

The RAD54 homolog B encoded by RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

Synonyms

RAD54B; DNA repair and recombination protein RAD54B; RAD54 homolog B

Gene ID

25788

UniProt

Q9Y620

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RAD54B. AA range:241-290

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, ELISA

Validated Applications

IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5438-1.pdf

Subcellular Location

Nucleus .

Other Product Names

RAD54B; DNA repair and recombination protein RAD54B; RAD54 homolog B

Gene ID (Human)

25788

SwissProt (Human)

Q9Y620

Available Sizes

Curated Selection

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