PRP6 rabbit pAb

The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

O94906

Swiss Prot

O94906

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PRPF6. AA range:747-796

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

110kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

110kD

Fragment

IgG

Subcellular Location

Nucleus, nucleoplasm . Nucleus speckle . Localized in splicing speckles. .

Other Product Names

PRPF6; C20orf14; Pre-mRNA-processing factor 6; Androgen receptor N-terminal domain-transactivating protein 1; ANT-1; PRP6 homolog; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein