Rab 38 rabbit pAb

Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. PTM: Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated. similarity: Belongs to the small GTPase superfamily. Rab family. tissue specificity: Expressed in melanocytes.

Product Specifications

Background

Function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1., PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated., similarity:Belongs to the small GTPase superfamily. Rab family., tissue specificity:Expressed in melanocytes.

UniProt

P57729

Swiss Prot

P57729

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

26kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

26kD

Fragment

IgG

Subcellular Location

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991) . .