LDOC1 rabbit pAb
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
O95751
Swiss Prot
O95751
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells
Gene ID (Human)
23641
Available Sizes
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