Tensin-2 (phospho Tyr483) rabbit pAb

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Product Name Alternative

TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

UniProt

Q63HR2

Swiss Prot

Q63HR2

Reactivity

Human; Mouse

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Tensin-2 (phospho Tyr483)

Target

Tensin-2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

152kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

152kD

Fragment

IgG

Subcellular Location

Cell junction, focal adhesion . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427) . .