NACAD rabbit pAb
Function: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). similarity: Belongs to the NAC-alpha family. similarity: Contains 1 NAC-A/B (NAC-alpha/beta) domain.
Product Specifications
Background
Product Name Alternative
NACAD; KIAA0363; NAC-alpha domain-containing protein 1
UniProt
O15069
Swiss Prot
O15069
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425
Target
NACAD
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
140kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
140kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus .
Other Product Names
NACAD; KIAA0363; NAC-alpha domain-containing protein 1
Gene ID (Human)
23148
Available Sizes
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